Dr. Anbarasu Karthikaichamy

Dr. Anbarasu Karthikaichamy

Postdoctoral Research Associate

Stony Brook University, NY, USA

Hi!

Anbarasu (Anbu) is a postdoc at the School of Marine and Atmospheric Sciences (SoMAS), Stony Brook University, New York. Anbu graduated from IITB-Monash Research Academy. In his Ph.D., Anbu studied the adaptation mechanisms of Microchloropsis gaditana under hyper-saline conditions using high-throughput OMICS techniques, such as proteomics and RNA-seq. Currently, he works with Prof. Jackie Collier (SoMAS) and Joshua Rest (Ecology and Evolution) on developing genetic tools for a wide taxonomic breadth of Labyrinthulomycetes (marine protists). Anbu is a semi-professional photographer, and a die-hard fan of Arsenal FC.

Interests

  • Microbial Stress Response
  • Marine Biotechnology
  • Molecular toolkits
  • Transcriptomics and Proteomics
  • Photography

Education

  • PhD in Microalgal Stress Response, 2019

    IITB-Monash Research Academy

  • MTech in Biopharmaceutical Technology, 2013

    Anna University, Chennai, India

  • BTech in Biotechnology, 2011

    Mepco Schlenk Engineering College, Sivakasi, India

Experience

 
 
 
 
 

Postdoctoral Research Associate

SoMAS, Stony Brook University

Aug 2019 – Present New York, USA

Responsibilities include:

  • Developing Molecular Tools
  • Comaparative Mitogenome Analysis
  • Bothrosome Formation in Aurantiochytrium
 
 
 
 
 

Graduate Teaching Assistant

Indian Institue of Technology Bombay

Jan 2014 – May 2016 Mumbai, India

Undergraduate lab sessions:

  • Simple distilation
  • Convective heat transfer
  • Enzyme kinetics of invertase
 
 
 
 
 

Master Student Research Assistant

Centre for Biotechnology, Anna University, Chennai, India

Apr 2012 – May 2013 Chennai, India
Studied the effect of a plant derived compound on mTOR and c-Src signalling in estrogen induced triple-negative breast cancer cell line.
 
 
 
 
 

Student Research Assistant

Gene Expression Lab, Mepco Schlenk Engineering College, Sivakasi

Dec 2010 – Apr 2011 Sivakasi, India
Employed RNase P RNA (RPR) gene to investigate the phylogeny of structural domains in 150 strains of Leptospira spp.

Awards & Honors

Best Ph.D. thesis award nomination

Molecular Plasticity of Microalgal Stress Response Oct 2019
Nominated by thesis examiners for the best Ph.D. thesis award at the August 2020 convocation.

Best 3 Minute Thesis Talk

Stress response in Microalgae Mar 2018
Presented at the Research Scholars’ Symposium 2018, Department of Chemical Engineering, IIT Bombay.

Travel Grant ‘17

11th International Phycological Congress, Szczecin, Poland Aug 2017
Travel grant awarded by MGE, Monash University, Melbourne, Australia.

Travel Grant ‘16

10th Algal Biomass Organization summit, Phoenix, AZ, USA Oct 2016
Travel grant awarded by the IITB-Monash Research Academy, Mumbai, India.

Gold Medal

Centre for Biotechnology, Anna University, Chennai Mar 2014
Highest CPI in M.Tech Biopharmaceutical Technology from Anna University, Chennai.

Lectureship (36th rank)

Council for Scientific and Industrial Research, India Jun 2012
Awarded Lectureship satus by CSIR, Govt. of India for qualifying the national level examination.

Projects

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All Labyrinthulomycetes Algal stress response Breast cancer Leptospira

Molecular toolkit for marine protists

Labyrinthulomycetes are osmoheterotrophic unicellular eukaryotes that play fungus-like roles in marine ecosystems and are also used biotechnologically in the production of essential omega-3 polyunsaturated fatty acid dietary supplements. Our long-term goal is to develop tools and techniques that enable functional genomic studies in marine protists.

DIA-based proteomic approach towards understanding the acclimation strategy of Microchloropsis gaditana CCMP526 in hypersaline conditions

Salinity is one of the significant factors that affect growth and cellular metabolism, including photosynthesis and lipid accumulation, in microalgae and higher plants. Microchloropsis gaditana CCMP526 can acclimatize to different salinity levels by accumulating compatible solutes, carbohydrates, and lipids as an energy storage molecule.

Temporal acclimation of Microchloropsis gaditana CCMP526 in response to hypersalinity

Evaporation from culture ponds and raceways can subject algae to hypersalinity stress, and this is exacerbated by global warming. We investigated the effect of salinity on a marine microalga, Microchloropsis gaditana, which is of industrial significance because of its high lipid-accumulating capability.

Time for multiple protein extraction methods in proteomics?

Proteomics has become a valuable tool for investigating many aspects of cell and organismal biology. However, a fundamental requirement for an accurate examination of the protein complement of cells is an efficient method for extracting the proteins.

Understanding the Molecular Significance of c-Src and mTor in Estrogen Mediated Breast Cancer Proliferation – an Invitro Study

Estrogen plays a major role through transcriptional regulation of its target genes. 17β-Estradiol, the predominant circulating estrogen, is known to be a major causative factor in the tumorigenesis of breast cancer.

Evolution of the RNase P RNA structural domain in Leptospira spp.

We have employed the RNase P RNA (RPR) gene, which is present as single copy in chromosome I of Leptospira spp. to investigate the phylogeny of structural domains present in the RNA subunit of the tRNA processing enzyme, RNase P.

Posters and Talks

Algae that grows on toxic gas and a reactive metal!

May 18, 2018 9:00 AM — 5:00 PM VMCC, IIT Bombay
Anbarasu Karthikaichamy
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Temporal Acclimation of Microchloropsis gaditana CCMP526 in resposne to hyper-osmolarity

Evaporation from open culture ponds and raceways can subject algae to salinity stress, and this is exacerbated by global warming. …
Aug 13, 2017 9:00 AM — Aug 19, 2017 4:00 PM University of Szczecin, Poland
Anbarasu Karthikaichamy
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An Investigation of Extraction Methods for Proteomic Analysis of Nannochloropsis gaditana CCMP526

Proteomics has become a valuable tool for investigating many aspects of cell and organismal biology. However, a fundamental requirement …
Oct 23, 2016 9:00 AM — Oct 27, 2016 4:00 PM Renaissance Glendale Phoenix Hotel & Spa
Anbarasu Karthikaichamy
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Publications

A Data-Independent-Acquisition-based proteomic approach towards understanding the acclimation strategy of Microchloropsis gaditana CCMP526 in hypersaline conditions

Salinity is one of the significant factors that affect growth and cellular metabolism, including photosynthesis and lipid accumulation, …
Anbarasu Karthikaichamy, John Beardall, Ross Coppel, Santosh Noronha, Dieter Bulach, Ralf B Schittenhelm, Sanjeeva Srivastava
PDF Project DOI

Non-photochemical quenching, a non-invasive probe for monitoring microalgal grazing- an early indicator of predation by Oxyrrhis marina and Euplotes sp.

Microalgae are major primary producers in aquatic environments, and many synthesize an array of industrially important biomolecules …
Pranali Deore, Anbarasu Karthikaichamy, John Beardall, Santosh Noronha
PDF Project DOI

Temporal acclimation of Microchloropsis gaditana CCMP526 in response to hypersalinity

Evaporation from culture ponds and raceways can subject algae to hypersalinity stress, and this is exacerbated by global warming. We …
Anbarasu Karthikaichamy, Pranali Deore, Sanjeeva Srivastava, Ross Coppel, Dieter Bulach, John Beardall, Santosh Noronha
Project DOI

Time for Multiple Extraction Methods in Proteomics? A Comparison of Three Protein Extraction Methods in the Eustigmatophyte Alga Microchloropsis gaditana CCMP526

Proteomics has become a valuable tool for investigating many aspects of cell and organismal biology. However, a fundamental requirement …
Anbarasu Karthikaichamy, Pranali Deore, Vineeta Rai, Dieter Bulach, John Beardall, Santosh Noronha, Sanjeeva Srivastava
PDF Project DOI

Multi-omics Frontiers in Algal Research- Techniques and Progress to Explore Biofuels in the Postgenomics World

Current momentum of microalgal research rests extensively in tapping the potential of multi-omics methodologies in regard to …
Vineeta Rai, Anbarasu Karthikaichamy, Debasish Das, Santosh Noronha, Pramod P Wangikar, Sanjeeva Srivastava
PDF Project DOI

Evolution of the RNase P RNA structural domain in Leptospira spp.

We have employed the RNase P RNA (RPR) gene, which is present as single copy in chromosome I of Leptospira spp. to investigate the …
Vigneshwaran Ravishankar, Ahmed Ahmed, Ulaganathan Sivagnanam, Krishnaraja Muthuraman, Anbarasu Karthikaichamy, Herald A Wilson, Ajay Devendran, Rudy A Hartskeerl, Stephen ML Raj
PDF Project DOI

Recent Posts

Apr 19, 2018 3 min read

Using salt to manipulate algae

There is too much salt in the soup!

Let’s connect!

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